You need to be organized about it. If you've got 50+ colors, some will be similar to one another. You need a way to keep your symbols and colors straight. If you're lucky, it's a pdf pattern you can put in pattern keeper. If not, just keep the paper with the symbols near to your colors. I use one of these plastic floss holders for holding colors (https://a.co/d/0fMu89wl), but I used to make my own with a hole punch and cardstock. That way lets you put the symbol with the color too. Also, as someone currently suffering from too small of a piece of fabric, I recommend more like 5 inches around. Will give you more leeway for not quite perfect centering and for framing later.
I get that way sometimes!! So I tend to do a 10x10 section. I mostly do a row at a time in the 10x10 section. I move the thread down to the next row, further on down, or I end the thread. It just depends where the next square is. I don’t travel longer than 10 squares. Rarely I will park a thread to the right of a 10x10 section. I park this thread using parking bobbins. Sometimes I just end it, and start a new thread when I get to that square if I don’t feel like doing parking bobbins. Either way works. Another thing that I do, if I have a lot of thread attached to my needle but I’m done with that color for now, I keep the needle attached and I stick it in the felt section of my floss organizer. It’s easy to grab it again when there’s confetti or something. The floss organizer: https://a.co/d/0fiqiunY When it doubt, move it down to the next row or next section, but not more than 10 squares away. That’s my main/first rule.
