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All right I do a fair amount of international travel, so here goes: Compression socks Soft fuzzy socks Hard bottomed slippers Comfrt Travel Essentials hoodie and pants. ( The amount of pockets and internal zippers are fantastic for keeping everything nearby and secure Cotton wide-band eye mask The softness and the width makes it much easier to sleep 2 large bags of individually wrapped Ghiradelli or other "nice" chocolates. Give them to the Stewardess nearest your seat as you get on the plane, They'll make sure you're taken care of the rest of the flight. Make sure you know what row you're sitting in, they'll ask. Pajamas / sleep bra. Immodium, Gasx, heartburn medicine, Pepto ... Nothing worse than gastrointestinal distress on a plane High DB earplugs, for when you're not wearing noise cancelling headphones and want soft silence Chapstick chapstick chapstick Travel neck scarf / turtle neck wrap. I find them better than the pillows, just make sure you wrap them really tight and high on your neck to hold your head. Magnetic anker charger. That way you can easily charge your phone or other devices while staying plugged in. Saline spray (gets dry a.f.) I'll continue the list in a bit